Carlos Manterola; Josue Rivadeneira; Carla Salgado; Antonia Enríquez & Diego Lara

Renal cell carcinoma (RCC) worldwide has an incidence of 431,288 cases per year, causing 179,368 deaths in 2020. However, despite its incidence, the development of pancreatic metastasis (MP) from RCC is unusual. The aim of this manuscript was to report the case of a patient with a PM of a RCC. This is a 56-year-old female patient, underwent right nephrectomy 132 months earlier for RCC. While she was in adjuvant immunotherapy, in a routine imaging control, it was found a tumor lesion in the body and the tail of the pancreas. So, she underwent surgery, performing a corpora-caudal pancreatectomy with splenic preservation. Postoperative evolution was correct, without complications, and she was discharged on the 4th day after surgery. The report of the study of the surgical piece with an immunohistochemical study included, conclusive of PM of RCC. Currently, the patient is in good general condition and restarted chemotherapy with monoclonal antibodies. Frequent and prolonged follow-up of patients with a history of RCC facilitates timely diag- nosis and treatment of PM, facilitating the best prognosis for patients, with higher survival rates.

KEY WORDS: "Pancreatic Neoplasms"[Mesh]; "Pancreatic Neoplasms/secondary"[Mesh]; "Pancreatic Neoplasms/surgery"[Mesh]; "Carcinoma, Renal Cell"[Mesh]; "Carcinoma, Renal Cell/secondary"[Mesh].

MANTEROLA, C.; RIVADENEIRA, J.; SALGADO, C.; ENRÍQUEZ, A. & LARA, D. Metachronic pancreatic metastasis of a renal cell carcinoma. Case report. Int. J. Morphol., 41(5):1550- 1557, 2023.