Angiogenesis, a process by which new blood vessels are generated from pre-existing ones, is significantly compromised in tumor development, given that due to the nutritional need of tumor cells, pro-angiogenic signals will be generated to promote this process and thus receive the oxygen and nutrients necessary for its development, in addition to being a key escape route for tumor spread. Although there is currently an increase in the number of studies of various anti-angiogenic therapies that help reduce tumor progression, it is necessary to conduct a review of existing studies of therapeutic alternatives to demonstrate their importance.
KEY WORDS: Angiogenesis Celecoxib; COX2, Tumor; Anti-angiogenic therapy.
ROJAS, V. & ROA, I. Celecoxib: antiangiogenic and antitumoral action. Int. J. Morphol., 42(1):40-45, 2024.
