The Effect of Different Oral Root Canal Filling Materials on the Expression of Inflammatory Factors and Protease Related Molecules in Gingival Crevicular Fluid in Patient with Posterior Tooth Anatomy Defects

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Li Yu; Wenting Shan; Yifei Shi & Tao Su

Summary

The objective of this study was to investigate the effects of different oral root canal filling materials on the expression of inflammatory factors and protease related molecules in gingival crevicular fluid (GCF). A total of 90 patients with posterior tooth defects who underwent root canal therapy in our hospital were selected. They were divided into an observation group (group A) and a control group (group B) based on different root canal filling materials, with 45 teeth in each group. The group A patients were repaired with fiber post, composite resin combined with zirconia ceramic crown, while the group B patients were repaired with metal post core combined with metal ceramic crown. The clinical effect, periodontal index, restoration success rate, mastication efficiency, periodontal index, restoration effect, and the levels of GCF and Alkaline phosphatase (ALP) before and after restoration were compared between the two groups. The clinical efficacy of the group A was better than that of the group B patients. The success rate of repair and chewing efficiency in the group A were higher than those in the group B. The completeness rate, color matching rate, edge fit rate, edge coloring qualification rate, and gingival qualification rate of the group A patients were higher than those of the group B patients. After repair, the levels of GCF and ALP in both groups of patients were higher than before repair, and the group B was raised than the group A. The PLI, GI, and SBI indices of the group A patients were reduced than those of the group B patients. The application of fiber post, composite resin combined with zirconia porcelain crown restoration in patients with posterior tooth defects after root canal treatment can improve the success rate, chewing efficiency, and restoration effect, with little impact on changes in GCF and ALP levels in the body.

KEY WORDS: Composite resin; Fiber post; Repair effect; Tooth anatomy defect; Zirconia porcelain crown.

How to cite this article

YU, L.; SHAN, W.; SHI, Y. & SU, T. The effect of different oral root canal filling materials on the expression of inflammatory factors and protease related molecules in gingival crevicular fluid in patient with posterior tooth anatomy defects. Int. J. Morphol., 42(4):1458- 1463, 2024.