This study aimed to assess association between preeclampsia with trophoblast cells and serum level of b-human chorionic gonadotropin (β-hCG). Were compared 20 patients with preeclampsia and 20 control patients with respect to demographics, hematological parameters and the presence of trophopblast in placental samples. Patchy necrosis with loss of microvilli and gross thinning of the syncytium with distorted microvilli were seen in terminal villi of placentae of women with pre-eclampsia Syncytial cells at the molecular level crossings, especially at the level of βhCG in conjunction with the changes in the preeclampsia was made on the histopathological changes to clarify the villi.

KEY WORDS: Pre-eclampsia; Placenta; βhCG; Syncytiotrophoblast.