Delgado-Ramírez, J. L.; Aragón, H. J. & Pérez-Martínez, M.

Summary

We studied the population of mast cells (CC) present in anal sacs of adult and senile dogs by its count in tissue processed with the technique of embedding in paraffin and stained with toluidine blue. The average CC obtained for the group of adult dogs (n=12) was 18.16 ± 7.58 and for group of senile dogs (n=12) was 73.75 ± 16.29. When comparing the number of cells in both groups with Mann-Whitney U test were found to be significantly different (P0.0001), being higher in the group of senile dogs. The largest population of CC may be related to an increased susceptibility of senile dogs to inflammatory reactions in the tissue of the anal sacs caused by changes in diet, obesity and chronic diarrhea.

KEY WORDS: Dog; Apocrine anal glands; Mast cells; Age; Histology.

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